• Abiye Mulugeta Ophthalmology, glaucoma



Background: Trabeculectomy with mitomycin C has been performed for glaucoma patients in Menelik II Hospital for years but the outcome has never been evaluated.

Objective: To evaluate the tonometric outcome of primary trabeculectomy with Mitomycin-C in primary open angle glaucoma and pseudoexfoliative glaucoma patients.

Subjects and methods: A retrospective study of patients seen at Menelik II Hospital, 40 years and above, with primary open angle glaucoma and pseudoexfoliative glaucoma of any stage that underwent primary trabeculectomy with Mitomycin-C in 2014 was evaluated. The surgery was done by two glaucoma specialists.                              

Results: A total of 166 charts were revised; and 98 (59%) were males and 68 (41%) were females. Primary open angle glaucoma accounted for 52.4% and pseudoexfoliative glaucoma 47.6%. Majority of patients were between 50-79yrs of age (91%).The mean intraocular pressure before surgery was 31.4±8.4mmHg and 11.8±6.5mmHg six months after surgery. At 6month post-operative follow up, complete success was found to be 60.2% and qualified success 27.1%, failure 9.6% and Hypotony 3.0%; and the overall success 87.3%. The overall success at six month follow up was 88.5% in Primary open angle glaucoma patients and 86.1% in Pseudoexfoliative glaucoma patients.                                   

Conclusions: Primary trabeculectomy with Mitomycin-C is safe and has good short-term outcome in Ethiopian patients at Menelik II glaucoma patients. The procedure has comparable success in both Primary open angle glaucoma and Pseudoexfoliative glaucoma patients.

Key words: Primary open angle glaucoma, Pseudoexfoliative glaucoma, Mitomycin-C, Trabeculectomy, Intra ocular pressure.

Author Biography

Abiye Mulugeta, Ophthalmology, glaucoma

Assistant Professor

Department of Ophthalmology, School of Medicine, Addis Ababa University



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Original Article