PREGNANCY OUTCOME OF INDUCED LABOR IN TERM PREMATURE RUPTURE OF MEMBRANE IN THREE TEACHING HOSPITALS OF ADDIS ABABA.

  • Sisay Teklu Waji Addis Ababa University, College of Health Sciences, School of Medicine, Department of Obstetrics and Gynecology.
  • Haregewoin Mussie Damtew Addis Ababa University, College of Health Sciences, School of Medicine, Department of Obstetrics and Gynecology.

Abstract

Abstract

Background

Premature rupture of membranes(PROM), if not followed by natural labor or delivered with in limited time period, it will get complicated by infection and reduced amniotic fluid. These complications will negatively affect maternal and perinatal outcome. Several factors affect the success of labor induction in women with term PROM and the practice varies from institution to institution. This study compares the pregnancy outcome and success of induction of labor in women with term PROM, low BISHOP score, managed with direct oxytocin induction protocol and prostaglandin followed by oxytocin protocol.

Methodology

Facility based prospective comparative cross sectional study design was used on cases of term PROM, low BISHOP score in the three teaching hospitals of Addis Ababa University. As both protocols are practiced in these hospitals, mothers managed with direct oxytocin induction protocol were compared with those managed with prostaglandin and oxytocin protocol for induction of labor.

Results

From the total 98 term PROM with low BISHOP included in the study, 49 mothers were managed with direct oxytocin protocol while the remaining were managed with prostaglandin and oxytocin protocol. Increased cesarean delivery for failed induction and non-reassuring fetal heart pattern was observed in direct oxytocin protocol group.

Conclusion 

Prostaglandin cervical ripening reduces the burden of cesarean section in cases of term PROM with low BISHOP.

Key Words: Term PROM, Direct Oxytocin, Prostaglandin, Induction

Author Biographies

Sisay Teklu Waji, Addis Ababa University, College of Health Sciences, School of Medicine, Department of Obstetrics and Gynecology.
Associate Professor, Ob-Gy department, AAU
Haregewoin Mussie Damtew, Addis Ababa University, College of Health Sciences, School of Medicine, Department of Obstetrics and Gynecology.
Lecturer, Oby-Gyn department

References

References

Steven GG, Jennifer RN, Joe LS. Obstetrics: Normal and Problem Pregnancies 7th ed. Phyladelphia.: Elsevier; 2017.p 640- 657

, Bricker L, Peden H, Tomlinson A, Al-Hussaini T, Idama T, Candelier C, et al. Titrated low-dose vaginal and/or oral misoprostol to induce labour for prelabour membrane rupture: a randomized trial. BJOG 2008; 115:1503–1511

, Rijal H, Manandhar R, Pradhan N. A randomized study comparing intravaginal Prostaglandin (PGE2) with oxytocin for induction of labour in premature rupture of membrane at term. Nepal Med Coll J 2012; 14(3): 199-203

, Suk N, Yik C, Sze L, Terence T. Labour characteristics and uterine activity: misoprostol compared with oxytocin in women at term with prelabour rupture of the membranes BJOG 2000,107(2), pp. 222-227

, Mary H, Arne O, Dan F, Sheila H, Ellen H, Terri l. Myhr, et al. Induction of labor compared with expectant management for prelabor rupture of the membranes at term, the new England journal of medicine April 18, 1996 volume 334 number 16, pp: 1005-1010

Cuningham F, Leveno K, Bloom S, Sponge C, Dashe J, Hoffman B,editors 24th ed. Williams obstetrics .Dallas Texas :Mcgraw –Hill 2014.

, Bhaumik S, Noopur N, Shashwat N. a comparative study of labour induction with intravaginal misoprostol versus intravenous oxytocin in premature rupture of membranes beyond 36 weeks’ gestation international journal of medical science and public health | 2013 | vol 2 | issue 3

Premature rupture of membrane. ACOG Committee Opinion No. 160. American College of Obstetricians and Gynecologists. 2016.

, Management protocol on selected obstetrics topics federal democratic republic of Ethiopia ministry of health January, 2010, Premature/Pre-Labor Rupture of Membrane, p160-168

, Oliver E, Olabisi M, Paschal E, Felix O, Titi G, Chikezie N. Safety and efficacy of misoprostol in induction of labour in prelabour rupture of fetal membrane in Nigerian women: a multicenter study, Iranian Journal of Reproductive Medicine Vol.6. No.2. pp: 83-87, Spring 2008

, Endale T, Fantahun N, Gemeda D ,Hussen M. Maternal and fetal outcome in term premature rupture of membrane, world J Emerg Med. 2016 ;7(2) :147- 152

Published
2019-03-30
Section
Original Article