Primary Juvenile Open-angle Glaucoma, Clinical Features at Presentation to Tertiary Eye Center, Minelik II Hopsital, Addis Ababa, Ethiopia
Background: Primary juvenile open-angle glaucoma is a rare form glaucoma that affects young individuals below the age of 40 years. It is characterized by rapid progression of the disease with severely high intraocular pressure. The purpose of this study was described the clinical features of Ethiopian patients with this form of glaucoma at the time of presentation to tertiary eye center.
Methods: A retrospective cross-sectional medical record review of patients’ with the diagnosis of primary juvenile open-angle glaucoma of five years period between 2013- and 2017. Central tendency, measures of dispersion, frequency and percentage were calculated using SPSS version 21 statistical software.
Results: A total of 55 cases were included during the study period. The mean age was 27.0 + 7.7, range: 5 to 35 years. Vision reduction was the commonest presenting complaint in 26 (47.3%) and 17 (30.9%) cases were identified while presenting for other complaints. The mean intraocular pressure of 98 eyes with glaucoma with and without medication was 37.2 + 11.3 mm Hg, range, 15 - 69 mm Hg. Based on visual acuity <3/60 and central 10 degree involving visual field, bilateral and unilateral blindness was identified in 9 (16.4%) and 27 (49.1%) cases, respectively. Glaucomatous optic nerve head damage was advanced in 68 (69.4%) of the eyes.
Conclusion: Ethiopians with primary Juvenile open-angel glaucoma are presenting to ophthalmic evaluation at advanced stage of the disease with very high intraocular pressure and vision loss.
Key words: Juvenile open-angle glaucoma, intraocular pressure, glaucomatous optic nerve head