Outcome of renal allograft recipients at Saint Paul’s hospital millennium medical college, national kidney transplant center Addis Ababa, Ethiopia

  • Berhanu Worku

Abstract

Background: Kidney transplant is the current modality of choice as a renal replacement therapy due to superior patient survival and quality of life than both peritoneal and hemodialysis. The service is limited outside ofdeveloped countries due to the requirement for structured organization, extended expertise, and qualified supportive laboratory, as well as extensive health system service support in general.

Objective: The aim of the study is to describe renal allograftrecipient outcomes during the first two years following establishment of the national kidney transplant center in AddisAbaba, Ethiopia.

Methods: A retrospective review of the case records of all recipients of renal allografts at Saint Paul’sHospital MillenniumMedical College between September 2015 and August 2017 wasdone.

Results:52 live donor kidney transplants were performedover two years.The cause of native kidney diseases was unknown in majority(32.6%),while chronic glomerulonephritis accounted for 30.8%. One fourth of recipients were transfused at least once before transplant. There was no biopsy proven rejection episode. There was one early graft loss from unknown cause. Atleast one organ system was affected with drug side effects in nearly in all(96%), leucopenia occurring in one fourth(22%) was very serious.Death censored graft survival at one year is 97.5% while mean GFR at one week, three month, six month and one year was 73.1, 93.6, 95.6, and96ml/min, respectively.After successful kidney transplant pre-transplant hypertension subsided in 46.5% of patients.

Conclusion: Graft survival and graft function at one year, were excellent, and comparable to excellent centers worldwide.

Key Words – Ethiopia, kidney, transplant, outcome

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Published
2020-03-30