Magnitude of Metabolic Syndrome and Associated Factors Among Renal Transplant Recipients at St. Paul Hospital’s National Kidney Transplant Centre: A New Centre Experience; April to July, 2018.

  • Leja Hamza

Abstract

Introduction: Metabolic syndrome (MS) is a cluster of risk factors for cardiovascular diseases (CVD). It is also common in renal transplant recipients and is associated with increased risk of graft dysfunction and cardiovascular mortality. Its magnitude is not known in our Ethiopian patients.

Objective: To determine the magnitude of metabolic syndrome and associated factors.

Methods: Analytical cross-sectional design was used. Eighty-seven Ethiopian renal transplant recipients having follow-up at St. Paul Hospital’s National Kidney Transplant Centre were studied from May to July, 2018. A structured data collection format was used to collect data. ContextualizedWHO STEPS Instrument for Non-communicable Diseases Risk Factor Surveillance” was utilized for collecting data on behavioral risk factors, biophysical measurements and laboratory tests. 

 Results: Majority of the patients were males, 64 (73.6%). Most of them were young with mean age of 35.8 (+11.9) years. Hypertension (HPN) was the commonest component of MS accounting for 49 (56.3%) of cases. The magnitude of metabolic syndrome was 34.5%. Only central obesity (P. value = 0.046; AOR 39.1 (1.1, 141) and hyperglycemia (P=0.031; AOR 25.1(1.3, 467.8) were significantly associated with metabolic syndrome.

Conclusion and Recommendations: The magnitude of MS was high in our transplant recipients. However, only waist circumference and hyperglycemia were found to have significant association with MS. Comprehensive preventive strategies should be implemented for management of MS to minimize its impact.

Key Words: Metabolic syndrome, renal transplant, DM, HPN, Dyslipidemia, Central Obesity, Ethiopia.

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Published
2020-03-30