THE MAGNITUDE AND CLINICAL PROFILE OF GALLSTONE DISEASE IN AYDER REFERRAL HOSPITAL, MEKELLE, ETHIOPIA: A CROSS-SECTIONAL DESCRIPTIVE STUDY

Authors

  • Mizan Kidanu Woldemariam mekele University
  • Fasika Amdeslasie Gebrekirkos Mekele University, College of health Sciences, Department of Surgery

Abstract

Background: Gallstone disease constitutes a significant health problem in developed countries. While it was thought to be uncommon in Africa, it currently seems that the disease is more frequently seen than expected. The magnitude of gallstone disease is not well studied in Ethiopia. The purpose of this study is to determine the magnitude of the problem as seen in Ayder Referral Hospital in Mekelle.

Methods: A cross-sectional descriptive study was conducted during the period January 1, 2010 - December 31, 2013 at the Department of Surgery, Ayder Referral Hospital in Mekelle, Ethiopia. Data was obtained from chart records using a pretested structured questionnaire developed for the purposes of the study.

Results: A total of 225 patients were included in the study. The age group 30-49 years comprised one-half of the patients and over two-thirds (71.6%) of the patients were female. Abdominal pain was the predominant complaint, including right upper quadrant pain (74.7%), epigastric pain (20%), and left upper quadrant pain (4.9%). About one-third (34.7%) had radiation of the pain to the back and 15.6% to the shoulders. Fatty meal was identified as an exacerbating factor in 62.2% of the patients. One hundred and eighty-four patients were operated on; laparoscopy was done in 30.2%, and open cholecystectomy in 51.6%. Only two patients had a complicated immediate post-operative course.

Conclusion: This hospital based study result suggests that gallstone disease is not uncommon in the northern part of Ethiopia. The pattern and clinical profile of the disease is not different from what has been reported from other parts of Ethiopia and the rest of Africa. Well-designed epidemiological studies are required to determine the risk factors, the types of stones, the diagnostic value of radiological examination and the efficacy of laparoscopic management of gallstone disease.

 

Key words: Gallstone disease; Magnitude, Ethiopia

 

Author Biographies

Mizan Kidanu Woldemariam, mekele University

Assistant professor, De[partment of Surgery

Fasika Amdeslasie Gebrekirkos, Mekele University, College of health Sciences, Department of Surgery

Assistant Professor, and head of Medical Education Unit

References

Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology 1999; 117(3):632-9

Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology 2002; 122(5):1500-11

National Institutes of Health Consensus Conference. Gallstones and laparoscopic cholecystectomy. American Journal of Surgery 1993; 165:390-8.

Portincasa P, Moschetta A, Palasciano G. Cholesterol gallstone disease. Lancet 2006; 368(9531):230-9

Shaffer EA. Epidemiology of gallbladder stone disease. Best Pract Res Clin Gastroenterol 2006; 20(6):981-96

Russo MW, et al. Digestive and liver diseases statistics, 2004. Gastroenterology. 2004; 126(5):1448-53

Shrestha HG, Bajracharya M. Incidence of cholelithiasis and its correlation with cancer of gallbladder at TU Teaching Hospital. JNMA 1991; 29:264-7

Ganiyu A. Rahman: Cholelithiasis and Cholecystitis: Changing Prevalence in an African Community. J Natl Med Assoc 2005; 97:1534-8

Akute OO, Marinho AO, Kalejaiye AO, Sogo K. Prevalence of gallstones in a group of antenatal women in Ibadan, Nigeria. Afr J Med Med Sci 1999; 28(3-4):159-61

Getachew A. Epidemiology of gallstone disease in Gondar University Hospital, as seen in the department of radiology. Ethiop J Health Dev 2008; 22(2):206-11

Bekele Z, Tegegn K: Cholecystitis: The Ethiopian experience, a report of 712 operated cases from one of the referral hospitals. Ethiop Med J 2002; 40(3):209-16

Ersumo T: Gallstone disease in a teaching hospital, Addis Ababa: a 5-year review. Ethiop Med J 2006; 44(1):49-59

Diehl AK: Epidemiology and natural history of gallstone disease. Gastroentrol Clin North Am 1991; 20:1-19

Chung YJ, et al: Prevalence and risk factors of gallstones in a general health screened population. Korean Journal of Medicine 2007; 27:480-90

Shaffer EA. Epidemiology and risk factors for gallstone disease: Has the paradigm changed in the 21st century? Current Gastroenterology Reports 2005; 7(2):132-40

Bartoli E, Capron J P. Epidemiology and Natural History of Cholelithiasis. Rev Prat Journal 2000;50(19):2112-6

Davide Festi et al. Clinical manifestations of gallstone disease: Evidence from the multicenter Italian study on cholelithiasis (MICOL) Hepatology 1999; 30(4):839-46

Traverso LW. Clinical manifestations and impact of gallstone disease. American Journal of Surgery 1993; 165 (4):405-9

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2017-06-16

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