SEPTICEMIA, ITS BACTERIAL ISOLATES, DRUG SUSCEPTIBILITY PATTERNS AND ASSOCIATED FACTORS AMONG SUSPECTED WOMEN ATTENDING DELIVERY AT DILCHORA HOSPITAL, DIRE DAWA, EASTERN ETHIOPIA
Background: Puerperal sepsis is a major cause of maternal morbidity and mortality and is usually within the first 42 days after child birth and it’s the second cause of maternal morbidity and mortality in the resource poor countries.
Objective:The aim of the study was to assess the prevalence of septicemia, its Bacterial isolates drug susceptibility patterns and associated factors among suspected women attending delivery at Dil-chora referral hospital, Dire Dawa, Eastern Ethiopia from May 1 to July 30 /2016.
Method: Cross sectional study was conducted with a sample size of 441 women of the age group 15-49 years at Dil-chora hospital, Dire Dawa, Eastern Ethiopia from May 1 to July 30 /2016. Socio-demographic and clinical data variables were collected using structured interview questionnaire. Blood was collected aseptically and inoculated aerobically for 48 hours. Antimicrobial susceptibility patternof isolated bacteria was determined by Kirby Bauer disc diffusion method. Data analyzed using SPSS version 16; Binary logistic regression was used to measure the association. Significant variables were further adjusted using multivariate analysis.
Conclusion: The prevalence of septicemia was 12.9%. Coagulase negative staphylococci and E. coli were the predominant isolated bacteria. Most of bacterial isolates were resistant against commonly used antibiotics such as ampicillin, amoxicillin and tetracycline.
Key word: Septicemia, Puerperal sepsis, maternal septicemia, Antimicrobial resistance.
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