Clinical Findings and Medical Management of Hospitalized Patients with Rheumatoid Arthritis in Western Algeria: a Retrospective Study

Authors

  • Siheme OUALI Department of Biology, Djillali Liabes University of Sidi bel Abbes, Laboratory of Molecular Microbiology, Proteomics and Health, Algeria
  • Khalida ZEMRI Department of Biology, Djillali Liabes University of Sidi bel Abbes, Algeria
  • Ferial SELLAM National Research Center of Biotechnology. CRBT
  • Noria HARIR Department of Biology, Djillali Liabes University of Sidi bel Abbes, Algeria Laboratory of Molecular Microbiology, Proteomics and Health, Algeria
  • Zahira BENAISSA Department of Biology, Djillali Liabes University of Sidi bel Abbes, Algeria
  • Sid Tadj HEBRI Department of internal medicine, CHU Sidi BelAbbes,Algeria
  • Ouassini BENSABER Department of functional rehabilitation, CHU Sidi Bel Abbes, Algeria
  • Zouaoui NADJI Department of internal medicine, CHU Sidi BelAbbes,Algeria

Keywords:

Clinical Characteristics, Rheumatoid Arthritis Patients, Treatment, Western Algeria Region

Abstract

Introduction: Rheumatoid arthritis is the most common inflammatory rheumatic disease in adults and chronic autoimmune disease with a prevalence of 0.5% in the world. It is four times more frequent in women than in men. The aim of this study was to determine the clinical, para-clinical, and therapeutic parameters of patients with rheumatoid arthritis in Western Algerian region (Sidi bel Abbes area in particular).

Methods: We carried out a retrospective study based on medical records over 300 patients with RA diagnosed between 2015-2019 in the internal medicine department and functional rehabilitation department of the University Hospital of Sidi Bel Abbes. All data were processed and analyzed via SPSS 22.0 (Statistical Package for the Social Sciences, IBM Corporation; Chicago, IL. August 2013).

Results: out of all the enrolled participants in our study, 85.7 % were females and 14.3% were males, the mean age of diagnosis was 52,717±12,2273, ranging from 14 to 84 years old. The average time of disease duration was 4,173±3,9381 years. 53.7% of  the subjects had moderate activity, and 45% were menopausal. The main medical histories were high blood pressure (41%) type 2 diabetes  (84.7%), hypothyroiditis  (06%) and osteoporosis (4.7%).  81.3% of patients were seropositive and 46.51% of smokers had a highly seropositive ACPA(Anti Citrullinated Peptides Antibodies) (p=0.002).Most patients used DAMRDS (Disease Modifying Anti-Rheumatic Drug) as treatment.

 

Conclusion: Our study has shown that relatively older adults are commonly affected; majority presented in moderate stage of the disease and more than the half of our patients were seropositive.

 

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2021-06-29

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