BONE MINERAL DENSITY(BMD) MEASUREMENT USING CENTRAL DUAL ENERGY X-RAY ABSORPTIOMETRY (DEXA) IN ADULT ETHIOPIANS

Authors

  • Alpha Seifu
  • Biruk Lambisso Wamisho
  • Aden Ashenafi

Abstract

Introduction

Bone mineral density is  the amount of inorganic  mineral in bone tissue. Its’ measurement is an important screening investigation done to diagnose patients with osteoporosis. Osteoporosis is a metabolic disorder characterized by low Bone mineral density resulting in increased incidence of fragility fractures.

Objectives

This study is an attempt to establish a normative Bone mineral density data for the Ethiopian population

Methods

This is a uni-center-based retrospective study. We reviewed the Bone mineral density of 345 Ethiopian individuals measured with a Dual-energy X-ray absorptiometry.

 Results

The peak bone density in males was reached at the age of 20-29 years. The age-related decline in bone mineral density was about 0.62%per year at the lumbar spine and 1.01% per year at the femur neck from the age 30 to 70 years. The peak bone density in females was reached at the age of 20-39 years, the age r-related decrease in bone density was about 0.465% at the lumbar region and 1.41% at the femur neck region .

Conclusion

Although this study has outstanding draw backs we found that the Bone mineral density values of Ethiopian individual was higher than those established for Caucasian individuals. Its significance is in highlighting the importance of establishing a normative data so as to accurately diagnose, treat and follow osteoporosis.

Key words: Bone mineral density, osteoporosis, Ethiopian, DEXA scan, BMI

 

 

 

 

References

World Health Organization (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Technical Report Series 843. 1994;4:368–438.

Kroger H, Heikkinen J, Laitinen K, Kotaniemi A. Dual-energy X-ray absorptiometry in normal women: a cross-sectional study of 717 Finnish volunteers. Osteoporos Int 1992;2:135–140.

Karlsson MK, Gardsell P, Johnell O, Nilsson BE, Akesson K, Obrant KJ. Bone mineral normative data in Malm6, Sweden: comparison with reference data and hip fracture incidence in other ethnic groups. Acta Orthop Scand 1993;64:168–172.

Burger H, van Daele PLA, Algra D, et al. The association between age and bone mineral density in men and women aged 55 years and over: the Rotterdam Study Bone Miner. 1994;25:1–13.

Truscott JG, Simpson D, Fordham NJ. A suggested methodology for the construction of national bone densitometry reference ranges: 1,372 Caucasian women form four UK sites. Br J Radiol 1997;70:1245–1251.

Mazess RB, Barden HS, Jonhston C, et al. Spine and femur density using dual-photon absorptiometry in normal US white women. Bone Miner 1987;2:211–219.

Tobias JH, Cook DG, Chambers TJ, Dalzel N. A comparison of bone mineral density between Caucasian, Asian and AfroCaribbean women. Clin Sci 1994;87:587–591.

Mazess RB, Barden HS. Bone density of the spine and femur in adult white females. Calcif Tissue Int. 1999;65:91–99.

Mazess RB, Barden HS, Drinka PJ, Bauwens SF, Orwoll ESD, Bell NH. Influence of age and body weight on spine and femur bone mineral density in US white men. J Bone Miner Res 1990;6:645–652.

Omrani GR, Masoompour SM, Hamidi A, et al. Bone mineral density in the normal Iranian population: a comparison with American reference data. Arch Osteoporos 2006;1(1-2):29–39. 11.Chantler S, Dickie K, Goedecke JH, et al. Site-specific differences in bone mineral density in black and white premenopausal South African women. Osteoporos Int 2012;23(2):533–542.

Mgodi NM, Kelly C, Gati B, et al. Factors associated with bone mineral density in healthy African women. Arch Osteoporos. 2015;10:206.

Mazess RB, Barden HS. Bone density of the spine and femur in adult white females. Calcif Tissue Int 1999;65:91–99.

Looker AC, Johnston CC, Wahner HW, et al. Prevalence of low femoral bone density in older US women from HNANES III. J Bone Miner Res 1995;10:796–802.

Anderson JJB, Henderson RC. Dietary factors in the development of peak bone mass. In: Burckhardt P, Heaney RP, editors. Nutritional aspects of osteoporosis. New York: Raven Press 1991;3–19.

Bonjour JP, Theintz G, Law F, Slosman D, Rizzoli P. Peak bone mass. Osteoporos Int 1994;4(suppl 1):7–13.

Mazess RB, Barden HS. Bone density of the spine and femur in adult white females. Calcif Tissue Int 1999;65:91–99.

Looker AC, Johnston CC, Wahner HW, et al. Prevalence of low femoral bone density in older US women from HNANES III. J Bone Miner Res 1995;10:796–802.

Bonjour JP, Theintz G, Law F, Slosman D, Rizzoli P. Peak bone mass. Osteoporos Int 1994;4(suppl 1):7–13.

Molyvda-Athanasopoulou E, Sioundas A, Hatziioannou K. Dual energy X-ray absorptiometry reference data for Greek population. The impact on diagnosis of using various normal ranges for comparison. Eur J Radiol 2000;36(1):36–40.

Mazess RB, Barden HS, Drinka PJ, Bauwens SF, Orwoll ESD, Bell NH. Influence of age and body weight on spine and femur bone mineral density in US white men. J Bone Miner Res 1990;6:645–652.

Kroger H, Heikkinen J, Laitinen K, Kotaniemi A. Dual-energy X-ray absorptiometry in normal women: a cross-sectional study of 717 Finnish volunteers. Osteoporos Int 1992;2:135–140.

Karlsson MK, Gardsell P, Johnell O, Nilsson BE, Akesson K, Obrant KJ. Bone mineral normative data in Malm6, Sweden: comparison with reference data and hip fracture incidence in other ethnic groups. Acta Orthop Scand. 1993;64:168–172.

Burger H, van Daele PLA, Algra D, et al. The association between age and bone mineral density in men and women aged 55 years and over: the Rotterdam Study. Bone Miner. 1994;25:1–13.

Truscott JG, Simpson D, Fordham NJ. A suggested methodology for the construction of national bone densitometry reference ranges: 1,372 Caucasian women form four UK sites. Br J Radiol 1997;70:1245–1251.

Mazess RB, Barden HS, Jonhston C, et al. Spine and femur density using dual-photon absorptiometry in normal US white women. Bone Miner 1987;2:211–219.

Ross PD, He Y-F, Yates AJ, et al. Body size accounts for most differences in bone density between Asian and Caucasian women. Calcif Tissue Int 1996;59:339–343.

Bhudhikanok GS, Wang M-C, Eckert K, Matkin C, Marcus R, Bachrach LK. Differences in bone mineral in young Asian and Caucasian Americans may reflect differences in bone size. J Bone Miner Res 1996;11:1545–1556.

Davis JW, Ross PD, Wasnich RD. Relation of height and weight to the regional variations in bone mass among Japanese-American men and women. Osteoporos Int 1995;5:234–238.

Edlestein SL, Barrett-Connor E. Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol 1993;138:160–169.

Harris SS, Dawson-Hughes B. Weight, body composition, and bone density in postmenopausal women. Calcif Tissue Int 1996;59:428–432.

Ortolani S, Trevisan C, Bianchi ML, Gandolini G, Cherubim R, Polli EE. Influence of body parameters on female peak bone mass and bone loss. Osteoporos Int. 1993;3(Suppl 1):S61–S66.

Tobias JH, Cook DG, Chambers TJ, Dalzel N. A comparison of bone mineral density between Caucasian, Asian and AfroCaribbean women. Clin Sci 1994;87:587–591

Felson DT, Zhang Y, Hannan MT, Anderson JJ. Effects of weight and body mass index on bone mineral density in men and women: the Framingham Study. J Bone Miner Res 1993;8:567–573.

Dawson-Hughes B, Shipp C, Sadowski L, Dallal G. Bone density of the radius, spine, and hip in relation to percent of ideal body weight in postmenopausal women. Calcif Tissue Int 1987;40:3104.

El-Desouki M. Bone mineral density of the spine and femur in the normal Saudi population. Saudi Med J 1995;16:30–35

Chantler S, Dickie K, Goedecke JH, et al. Site-specific differences in bone mineral density in black and white premenopausal South African women. Osteoporos Int 2012;23(2):533–542.

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Published

2020-12-16