MUSCULOSKELETAL TUMORS AT ADDIS ABABA UNIVERSITY, ETHIOPIA: A 21 YEAR ANALYSIS AT THE ORTHOPAEDIC CENTER, TIKUR ANBESA SPECIALIZED HOSPITAL.
The burden of cancer is on the rise, according to WHO’s report the number of new cases is said to increase by about 70% over the next two decades. It is the second leading cause of death worldwide, and 2/3rd of these deaths are in low- and middle-income countries like Ethiopia. Musculoskeletal tumors refer to abnormal growths involving bone and the surrounding soft tissues. In Ethiopia, like that of rest of sub-Saharan nations estimates for the incidence of musculoskeletal tumors is increasing;
The source of information is the Orthopedic Center at Tikur Anbessa Specialized Hospital which is the Country’s largest and major diagnostic and treatment center for musculoskeletal tumors. The patients demographics and selected variables are recorded from their medical records onto Ms.Excel and then analyzed using IBM SPSS(V.24). The database spans from 1989 G.C upto 2009 G.C
There is a trend of rising case numbers, from less than ten cases in 1989 to more than a 100 cases per year in 2007 and 2008 each. Overall, the leading musculoskeletal tumors are soft tissue sarcomas at 66.3% followed by Osteosarcoma 18.5% which is the leading primary bone tumor in the study duration.
There is a need for establishing or strengthening population‐based Musculoskeletal tumor registry in the whole of Ethiopia to implement executive and evidence‐based national and regional cancer control programs.
Fitzmaurice C, Allen C, Barber RM, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study Global Burden of Disease Cancer Collaboration. JAMA Oncology. 2017; 3 : 524–48.
Okobia M. Cancer Care in sub-Saharan Africa – Urgent Need for Population–based Cancer Registries. http://www.ajol.info/index.php/ejhd/article/view/9848
Jemal A, Bray F, Forman D, et al. Cancer burden in Africa and opportunities for prevention. ACS 2012; 118 : 4372–84.
Parkin Parkin DM, Ferlay J, Hamdi-Cherif M et al. Cancer in Africa Epedimiology and prevention, What did we learn in the last 50 years. IARC 2003; 153 :268-276
Parkin DM, Bray F, Ferlay J, Jemal A. Cancer in Africa 2012. Cancer Epidemiol Biomarkers Prev. 2014;23(6):953–66.
M.Malawer M, Sternheim A. Operative techniques in orthopedic surgical oncology. In: M.Malawer M, C.Wittig J, Bickels J, editors. Philadelphia: LIPPINCOIT WILLIAMS &: WILKINS; 2012. p. 418.
Salaw ON, Babalola OM, Ed A, Mejabi JO, Fadim AA. Musculoskeletal tumors of the extremities: Challenges and outcome of management in a Nigeria Tertiary Hospital [Internet]. www.ajmhs.org/printarticle.asp?issn=2384
Inuwa M, Zakariyau L, Ismail D, Friday E, Ibrahim A, Mohammed A. Overview of extremity musculoskeletal neoplasms at the Ahmadu Bello University Teaching Hospital Zaria, Nigeria. Ann http://www.annalsafrmed.org/text.asp?2017/16/3/141/209087
Patrick C., Toy., Robert K., Heck Jr. Campbell’s operative orthopaedics . In: Frederick M, James H, S. Terry Canale, editors. 13th ed. Philadelphia: Elsevier; 2017: 918–93.
Ferreira N, Marais LC. Osteosarcoma presentation stages at a tumour unit in South Africa. South African Med J 2012;102(8):673–6.
Gerrand C, Athanasou N, Brennan B, et al. UK guidelines for the management of bone sarcomas. http://clinicalsarcomaresearch.biomedcentral.com/articles/10.1186/s13569-016-0047-1
Samoyo PTK, Nkya GZ, Minja FG, Temu RJ. Clinicopathological guide to malignant bone tumours: A retrospective analysis of the cancer registry at Kilimanjaro Christian Medical Centre in northern Tanzania. East Cent African J Surg. 2018; 28:22(2):24.
Bajpai J, Khanna N, Vora T, Gulia A, Laskar S, Puri A, et al. Analysis of bone and soft-tissue sarcomas registered during the year 2012 at Tata Memorial Hospital, Mumbai, with clinical outcomes [Internet]. Available from: www.indianjcancer.com/printarticle.asp?issn=0019-509X;year=2018;volume=55;issue=1;spage=37;epage=44;aulast=Bajpai
Aina OJ, Adelusola KA, Orimolade AE, Akinmade A. Histopathological pattern of primary bone tumours and tumour-like lesions in Ile-Ife, Nigeria. Pan Afr Med J. 2018;2:29.