ADHERENCE AND BARRIERS TO SECONDARY PROPHYLAXIS FOR RHEUMATIC HEART DISEASE AT TIKUR ANBESSA SPECIALIZED HOSPITAL

Share:
  • Articles
  • Submited: May 27, 2021
  • Published: March 29, 2022

Abstract

Introduction: Rheumatic heart disease (RHD) is one of the major causes of cardiovascular disease in developing countries. Secondary prophylaxis is effective for preventing recurrent acute rheumatic fever (ARF) and the progression of RHD. The purpose of the study was to assess adherence and barriers to use secondary prophylaxis for RHD at Tikur Anbessa Specialized Hospital (TASH).

Methods: Cross-sectional study was conducted from June 5, 2020, to September 4, 2020, at Tikur Anbessa Specialized Hospital, Ethiopia. A structured questioner was used for the data collection on awareness, adherence, and barriers for benzathine penicillin prophylaxis in adults with RHD. Data were analyzed using SPSS version 26.

Results: A total of 385 patients participated in this study, 305(79.6%) patients were aware about sore throat associated with heart disease, and about 288 (75.6%) patients know that benzathine penicillin prevents tonsillitis. Adherence rate was 77.9%. The main barriers for nonadherence in this study were the unavailability of medications, schedule forgetfulness, and health professionals’ refusal to inject benzathine penicillin. Increased age was found to have a significant association with adherence to B. penicillin. For each one-year increase in the age of patients with RHD, the adherence decreases by 3% [AOR= 0.97; 95% CI 0.95, 0.99], P value = 0.006)

Conclusion: Adherence level to monthly benzathine penicillin injection was low, which is below WHO recommendation. This study has revealed major barriers that affect adherence to secondary prophylaxis for RHD that can be used to develop interventions to improve adherence.

 

Downloads

Download data is not yet available.

References

  1. World Health Organization. Rheumatic Fever and Rheumatic Heart Disease: Report of a WHO expert Consultation, Geneva, 29 October-1 November, 2001. World Health Organization; 2004 Feb 4.
  2. Noubiap JJ, Agbor VN, Bigna JJ, Kaze AD, Nyaga UF, Mayosi BM. Prevalence and progression of rheumatic heart disease: a global systematic review and meta-analysis of population-based echocardiographic studies.
  3. Scientific reports. 2019 Nov 19;9(1):1-4.
  4. Yadeta D, Hailu A, Haileamlak A, Gedlu E, Guteta S, Tefera E, Tigabu Z, Tesfaye H, Daniel W, Mekonnen D, Zelalem M. Prevalence of rheumatic heart disease among school children in Ethiopia: A multisite echocardiography-based screening. International journal of cardiology. 2016 Oct 15;221:260-3.
  5. Yadeta D, Guteta S, Alemayehu B, Mekonnen D, Gedlu E, Benti H, Tesfaye H, Berhane S, Hailu A, Luel A, Hailu T. Spectrum of cardiovascular diseases in six main referral hospitals of Ethiopia. Heart Asia. 2017 Jul
  6. ;9(2).
  7. World Health Organization. Rheumatic fever and rheumatic heart disease. Report by the Director General. Seventy-First World Health Assembly. World Health Organization, Geneva, Switzerland. http://apps. who. int/gb/ebwha/pdf_files/WHA71/A71_25-en. pdf. 2018.
  8. Nkoke C, Luchuo EB, Jingi AM, Makoge C, Hamadou B, Dzudie A. Rheumatic heart disease awareness in the South West region of Cameroon: A hospital based survey in a Sub-Saharan African setting. Plos one. 2018
  9. Sep 25;13(9):e0203864.
  10. Mohammed K, Demissie WR, Gare MB. Adherence of rheumatic heart disease patients to secondary prophylaxis and main reasons for poor adherence at Jimma Medical Center. E Journal of Cardiovascular Medicine. 2019 Mar 1;7(1):22.
  11. Saxena A, Mehta A, Ramakrishnan S. Adherence to benzathine penicillin in children with rheumatic fever/rheumatic heart disease: results from an Indian pediatric RHD registry. Journal of the American College of Cardiology. 2015 Mar 17;65(10S):A2019-.
  12. Adem A, Gemechu TD, Jarso H, Reta W. Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study. Patient
  13. preference and adherence. 2020;14:2399.
  14. Petricca K, Mamo Y, Haileamlak A, Seid E, Parry E. Barriers to effective follow-up treatment for rheumatic heart disease in Jmma, Ethiopia: a grounded theory analysis of the patient experience. Ethiopian Journal of Health Sciences. 2009;19(1).
  15. Balbaa A, ElGuindy A, Pericak D, Yacoub MH, Schwalm JD. An evaluation of secondary prophylaxis for rheumatic heart disease in rural Egypt. Global Cardiology Science and Practice. 2015 Oct 6;2015(3):40.
How to Cite
Zewde, L., & Mekonnen, D. . (2022). ADHERENCE AND BARRIERS TO SECONDARY PROPHYLAXIS FOR RHEUMATIC HEART DISEASE AT TIKUR ANBESSA SPECIALIZED HOSPITAL. Ethiopian Medical Journal, 60(2). Retrieved from https://emjema.org/index.php/EMJ/article/view/1922

Send mail to Author


Send Cancel