Human fascioliasis,Fasciola hepatica,Liver Fluke, Eosinophilia, Extrahepatic

Brook Alemayehu
Assistant professor of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia
Zekewos Demissie
a:1:{s:5:"en_US";s:23:"Addis Ababa University ";}
Eyob Beyene
Department of Internal Medicine, Division of Infectious Disease, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
  • Articles
  • Submited: June 4, 2023
  • Published: September 25, 2023


Fascioliasis, a disease caused by liver flukes. It is one of the neglected zoonotic diseases. There are only a few reports of fascioliasis from Ethiopia and no case with predominant extrahepatic presentation has been reported so far. We report a case of young woman, who presented with a two weeks of dry cough and generalized pruritus. Her workup revealed marked eosinophilia and multiple, hypodense, and hypovascular hepatic lesions. An enzyme-linked assay became positive for Fasciola hepatica. Fasciola hepatica can present with predominant extra hepatic presentation and should be considered in patients presenting with urticaria, skin rash, cough and eosinophilia




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  1. Mas-Coma S. Epidemiology of fascioliasis in human endemic areas. J Helminthol. 2005 Sep;79(3):207-16. doi: 10.1079/joh2005296. PMID: 16153314.
  2. Webb CM, Cabada MM. Recent developments in the epidemiology, diagnosis, and treatment of Fasciola infection. Curr Opin Infect Dis. 2018 Oct;31(5):409-414. PMID: 30113327.
  3. Dermauw V, Muchai J, Al Kappany Y, Fajardo Castaneda AL, Dorny P. Human fascioliasis in Africa: A systematic review. PLoS One. 2021 Dec 9;16(12):e0261166. doi: 10.1371/journal.pone.0261166. PMID: 34882738; PMCID: PMC8659297.
  4. Fentie T, Erqou S, Gedefaw M, Desta A. Epidemiology of human fascioliasis and intestinal parasitosis among schoolchildren in Lake Tana Basin, northwest Ethiopia. Trans R Soc Trop Med Hyg. 2013 Aug;107(8):480-6. doi: 10.1093/trstmh/trt056. PMID: 23843557.
  5. Adachi S, Kotani K, Shimizu T, Tanaka K, Shimizu T, Okada K. Asymptomatic fascioliasis. Intern Med. 2005 Sep;44(9):1013-5. PMID: 16258225.
  6. López-Vélez R, Domínguez-Castellano A, Garrón C. Successful treatment of human fascioliasis with triclabendazole. Eur J Clin Microbiol Infect Dis. 1999 Jul;18(7):525-6. PMID: 10482035.
  7. Marcos LA, Terashima A, Gotuzzo E. Update on hepatobiliary flukes: fascioliasis, opisthorchiasis and clonorchiasis. Curr Opin Infect Dis. 2008 Oct;21(5):523-30.
  8. Caravedo MA, Cabada MM. Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis,
  9. Treatment, and Control. Res Rep Trop Med. 2020 Nov 26;11:149-158.
  10. Kabaalioğlu A, Cubuk M, Senol U, Cevikol C, Karaali K, Apaydin A, Sindel T, Lüleci E. Fascioliasis: US,CT, and MRI findings with new observations. Abdom Imaging. 2000;25:400–404.
  11. Koç Z, Ulusan S, Tokmak N. Hepatobiliary fascioliasis: imaging characteristics with a new finding. Diagn Interv Radiol. 2009 Dec;15(4):247-51.
How to Cite
Alemayehu, B., Demissie, Z., & Beyene, E. (2023). Human fascioliasis,Fasciola hepatica,Liver Fluke, Eosinophilia, Extrahepatic . Ethiopian Medical Journal, 61(4). Retrieved from

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