MAGNITUDE, CLINICAL PROFILE AND HOSPITAL OUTCOME OF CHRONIC LIVER DISEASE AT ST. PAULâ€™S HOSPITAL MILLENNIUM MEDICAL COLLEGE, ADDIS ABABA, ETHIOPIA
Background: Chronic liver disease /CLD/ is one of the major causes of admission in hospitals. It has a wide spectrum of presentation, causes and requires organized treatment approaches to reduce the mortality.
Objectives: To assess the prevalence of CLD among medical admissions, clinical presentations, types of management received and hospital outcomes in St. Paulâ€™s Hospital Millennium Medical College.
Materials and Methods: Data was collected retrospectively from January 20, 2009 - September 11, 2014 G.C in admitted patients from medical wards and ICU. Questionnaire was comprised of basic demographic data, clinical symptoms and signs, laboratory results, type of treatment received and hospital outcomes.
Results: The proportion of CLD in the medical wards during the study period was 2.3%. Men comprised 91.5% of admission due to CLD. The most common clinical presentations were abdominal distension and jaundice with 70% and 33.3% prevalence respectively. From viral causes, Hepatitis B virus was diagnosed in 44.4 % and 18% of the causes were due to Hepatitis C Virus; 3 individuals had mixed infection. Patients received only supportive treatment and 41% passed away during their hospital stay and only 28% of were discharged improved.
Conclusions:Chronic liver disease is prevalent in the study and associated with highÂ mortality. Despite the burden of the disease, at the time of the study, no antiviral or other targeted treatment was provided in the hospital. We recommend further study to assess the cause of the increased mortality and provision of anti-viral and other targeted therapies.
Key words: CLD, HBV, HCV, Hepatocellular Cancer, Ethiopia.
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