• Yazezew Kebede Kiros Internal medicine and Gastroenterology
  • Beniam Tsegay
  • Hagos Abreha


Background: Gastrointestinal endoscopy service in Ethiopia is mainly limited to the capital city Addis Ababa. The service started in Ayder referral hospital, Mekelle, in 2011 after two physicians obtained six weeks unstructured, on-site training where each of them was able to perform only 20 supervised procedures. The major objective of this study was to determine the pattern of endoscopic findings of diseases in our endoscopy practice at Ayder referral hospital.

Methods: The study design was a facility-based retrospective cohort study. The endoscopy registry was interrogated retrospectively and analyzed using descriptive statistics.

Results: A total of 2,486 patients’ endoscopic examinations were included in the study. Upper and lower gastrointestinal endoscopy totalled 1,994 and 492 procedures, respectively. Seventy four percent of colonoscopies and 58.7% of esophago-gastroduodenoscopies (EGD) were performed on male patients. The mean, minimum and maximum age of the study subjects was 40, 1 and 94 years of age respectively. The common EGD findings were erythema of gastric mucosa in 489 (24.5%), varices in 253 (12.7%), gastric cancer in 188(9.4%), peptic ulcer disease in 176 (8.8%) and gastroesophageal reflux disease in 96 (4.8%). The common colonoscopic findings were colorectal cancer in 114(23.2%), non-specific erythema of colonic mucosa in 78 (15.9%) and internal hemorrhoids in 37(7.5%).There was a poor correlation (0.5-57.7%) between clinical and endoscopic diagnosis; however, endoscopic diagnosis showed significant correlation (73%-100%) with histological diagnosis.

 Conclusion: Our findings are in agreement with those of other similar cohort studies. Hence, endoscopy service in such a resource-limited setting may be expanded by giving short-term, unstructured, onsite training to physicians.

Key words: Gastrointestinal endoscopy, Ayder Referral Hospital, Mekelle University, histological, clinical, diagnosis


Author Biographies

Yazezew Kebede Kiros, Internal medicine and Gastroenterology

Assistant professor

Mekelle University

School of Medicine

department of Internal medicine 

Beniam Tsegay

Assistant professor

Mekelle University

School of Medicine

department of Pathology


ASGE taskforce on ensuring competence in Endoscopy. Ensuring competence in Endoscopy. 2011:5-6

Taye M, Kassa E, Mengesha B, Gemechu T, Tsega E. Upper gastrointestinal endoscopy: a review of 10,000 cases. Ethiop Med J. 2004;42(2):97-107.

Malu AO, Wali SS, Kazmi R, Macauley D, Fakunle YM. Upper gastrointestinal endoscopy in Zaria, northern Nigeria. West Afr J Med. 1990;9(4):279-84.

Olokoba AB, Olokoba LB, Jimoh AA, Salawu FK, Danburam A, Ehalaiye BF. Upper gastrointestinal tract endoscopy indications in northern Nigeria. J Coll Physicians Surg Pak. 2009;19(5):327-8. doi: 05.2009/JCPSP.327328.

Dakubo JC, Clegg-Lamptey JN, Sowah P. Appropriateness of referrals for upper gastrointestinal endoscopy. West Afr J Med. 2011;30(5):342-7.

Olokoba AB, Obateru OA, Bojuwoye MO, Olatoke SA, Bolarinwa OA, Olokoba LB. Indications and findings at colonoscopy in Ilorin, Nigeria. Niger Med J. 2013;54(2): 111–4.

Lodenyo H, Rana F, Mutuma GZ, Kabanga JM, Kuria JK, Okoth FA. Patterns of upper gastrointestinal diseases based on endoscopy in the period 1998-2001. Afr J Health Sci. 2005; 12(1-2):49-54.

Misauno MA, lsmaila BO, Usman BD, Abdulwahab-Ahmed A, Achinge GI. Spectrum of endoscopically diagnosed upper gastrointestinal diseases in Jos. Sahel Med J. 2011; 14(2):63-6.

Tachi K, Nkrumah KN. Appropriateness and diagnostic yield of referrals for Oesophagogastroduodenoscopy at the Korle Bu Teaching Hospital. West Afr J Med. 2011;30(3):158-63.

Segni M, Birgitta S, Venance P, Gibson S. Upper gastrointestinal endoscopic findings and prevalence of Helicobacter pylori infection among adult patients with dyspepsia in northern Tanzania. Tanzan J Health Res. 2014;16(1):16-22.

Agbakwuru EA, Fatusi AO, Ndububa DA, Alatise OI, Arigbabu OA, Akinola DO. Pattern and validity of clinical diagnosis of upper gastrointestinal diseases in south-west Nigeria. Afr Health Sci. 2006;6(2):98-103.

Rashmi K, Horakerappa MS, Karar A, Mangala G. A study on histopathological spectrum of upper gastrointestinal tract endoscopic biopsies. Int J Med Res Health Sci. 2013;2(3):418- 24.

Islam SMJ, Mostaque Ahmed ASM, Ahmad MSU, Hafiz S. Endoscopic and Histologic Diagnosis of Upper Gastrointestinal Lesions, Experience in a Port City of Bangladesh. Chattagram Maa-O-Shishu Hospital Medical College Journal 2014; 13(3):11-4

Sheikh BA, Hamdani SM, Malik R. Histopathological spectrum of lesions of upper Gastrointestinal tract- A study of endoscopic biopsies. GJMEDPH 2015; 4(4):1-8

Bane A, Ashenafi S, Kassa E. Pattern of upper gastrointestinal tumors at Tikur Anbessa Teaching Hospital in Addis Ababa, Ethiopia: a ten-year review. Ethiop Med J. 2009; 47(1):33-8.




How to Cite

Kiros, Y. K., Tsegay, B., & Abreha, H. (2017). ENDOSCOPIC AND HISTOPATHOLOGICAL CORRELATION OF GASTROINTESTINAL DISEASES IN AYDER REFERRAL HOSPITAL, MEKELLE UNIVERSITY, NORTHERN ETHIOPIA. Ethiopian Medical Journal, 55(4). Retrieved from https://emjema.org/index.php/EMJ/article/view/480



Original Article