• Abiyu Mekonnen Gebrehiwot Haramaya University
  • Beyene Petros Addis Ababa University


Aims/Purpose: TB outbreaks emerge occasionally in long-term care facilities, including various educational establishments. This study was designed to determine the five years overall prevalence and trend of tuberculosis and associated factors among students at Adama Science and Technology University and Addis Ababa University 6 kilo campus.

Methods: A five years retrospective  study was conducted on students’ medical records from  TB Directly Observed Treatment Short Course (DOTS) clinics. The overall prevalence and the trend of smear positive, smear negative and extra pulmonary TB cases were determined. Odds ratio with 95 percent C.I was calculated using the Logistic Regression model. Furthermore, an in-depth assessment of AFB sputum smear examination practices of the lab staffs were  conducted using the WHO's  standard checklist.

Results: A total of 112 and 263  TB cases were recorded in Addis Ababa University (AAU), 6 kilo campus and Adama Science and Technology University (ASTU), respectively. There was a statistically significant difference in prevalence  of TB among students  in ASTU compared to that in AAU, 6 kilo campus [AOR:  2.881, 95% CI (1.76-4.71)]. An in-depth interview with the respective University Clinic lab chiefs indicated that the  University  labs were not linked with  the national tuberculosis program and hence quality of sputum smear microscopy examination practices in both study Universities were found to be poor. 

Conclusions: The numbers of tuberculosis cases observed in this study were high. Governmental and Nongovernmental agencies involved in  TB control  must consider higher education institutions as focal points  for prevention and elimination of tuberculosis in Ethiopia.

Author Biographies

Abiyu Mekonnen Gebrehiwot, Haramaya University

PhD fellow at Addis Ababa University, College of Natural Sciences, Department of Microbial, Cellular and Molecular Biology, and an Assistant professor of Tropical and Infectious Diseases, College of Health and Medical Sciences, Haramaya University, Ethiopia

Beyene Petros, Addis Ababa University

Professor of Biomedical Sciences at College of Natural Sciences, Department of Microbial, Cellular and Molecular Biology


Federica B, Francesco M and Andrea D. Immunology of Tuberculosis. Mediterr J Hematol Infect Dis. 2014; 6(1): e2014027, DOI: 10.4084/MJHID.2014.027


Who. Global tuberculosis report 2012. Geneva, Switzerland: WHO; 2012.


The Lodi Tuberculosis Working Group. A school-and community-based outbreak of Mycobacterium tuberculosis in northern Italy. Epidemiol Infect. 1994;113:83–93.


Zhang S, Hong Yan H, Zhang J, Zhang T, Li X and Zhang Y. The experience of college students with pulmonary tuberculosis in Shaanxi, China: a qualitative study BMC Infectious Diseases. 2010; 10:174 doi: 10.1186/1471-2334-10-174


Stein-Zamir C, Volovik I, Rishpon S, Atamna A, Lavy A, and Weiler-Ravell D. Tuberculosis outbreak among students in a boarding school. Eur Respir J. 2006;28(5):986–91.


Moges B, Amare B, Yismaw G, et al. Prevalence of tuberculosis and treatment outcome among university students in Northwest Ethiopia: a retrospective study. BMC Public Health. 2015; 15:15. DOI 10.1186/s12889-015-1378-1.


Dye C. and Williams B. Eliminating human tuberculosis in the twenty-first century. Journal of The Royal Society Interface. 2008; 5: 653-662.


Dye C. and Borgdorff M. Global Epidemiology and Control of Tuberculosis, in Handbook of Tuberculosis: Clinics, Diagnostics, Therapy and Epidemiology. Kaufmann S and Helden P, Editors. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim; 2008.


Manual of Tuberculosis and Leprosy and TB/HIV prevention and control, F.M.o. Health, Editor, EthioTikur Printing Press: Addis Ababa, Ethiopia; 2008.


Ethiopia, M.o.H.o., First Ethiopian National Population Based Tuberculosis Prevalence Survey; 2011.


Kate A and Philip R. The Purposes and Practices of Quality Assurance in Ethiopian Higher Education: Journey, Adaptation and Integration. International Journal of Business Anthropology. 2012: 3(2).


Global Tuberculosis report, 2014. Key indicators for the WHO African region. Estimates of mortality, prevalence and incidence (www.who.int/tb/data/)


WHO: 44th World Health Assembly (WHA/1991/REC/1); supplemented by 53rd World Health Assembly, Report by the Director General, Provisional Agenda Item 12.1, A53/5. Geneva, Switzerland: World Health Organization; 2000.


Yamasaki-Nakagawa K, Ozasa N, Yamada N, et al. Gender difference in delays to diagnosis and health care seeking behavior in a rural area of Nepal. Int J Tuberc Lung Dis. 2001; 5:24–31.


Abiyu M. Smear-positive pulmonary tuberculosis and AFB examination practices according to the standard checklist of WHO’s tuberculosis laboratory assessment tool in three governmental hospitals, Eastern Ethiopia. BMC Research Notes. 2014; 7:295. doi:10.1186/1756-0500-7-295


WHO: Global tuberculosis control: surveillance, planning, financing: WHO report 2008. 20 Avenue Appia, 1211 Geneva 27, Switzerland: WHO/HTM/TB/ 2008.393, WHO Press, World Health Organization; 2008.







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